Agm2S aims to facilitate the interpretation of complex glycan tandem mass spectrometry datasets by combining theoretical fragmentation with automated matching to experimental high-resolution mass spectra. Glycan structures can be provided either as a graphical representation including monosaccharide units and linkages, or as condensed IUPAC notation. Users can define charge states, adducts, chemical modifications and fragmentation rules according to their experimental setup. Based on these inputs, Agm2S generates extensive sets of theoretical fragment ions and compares them to experimental MS/MS data, enabling the annotation of a large fraction of observed signals, including isobaric fragment ions arising from different fragmentation pathways. Agm2S is currently under active development. The core concepts and computational framework are implemented, and validation is ongoing on representative glycan datasets covering different sizes, ionization modes and adduct types. At this stage, the application should be considered a work in progress. New features, refinements and documentation will be progressively added as development and benchmarking continue.